The star has given the complete sum of his twenty-five thousand pound award prize money to the trust for venues, which works to save the UK's independent live music spots.
He was awarded the award on 16 October as his latest record his work was declared the top album of the previous year.
The musician has chosen to donate the funds to the MVT, in recognition of the vital role small stages had in his initial steps.
"I personally couldn't be pursuing my current career if it hadn't been for all the performances I performed around the region, and elsewhere, when I was just getting going," remarked Sam Fender. "These venues are legendary, but they are facing challenges."
Beginning in 2023, at least 150 of these spaces have shut down – about one-sixth of the total UK scene.
Recently, major artists such as Pulp, Coldplay, Katy Perry and Ed Sheeran have all supported the trust in its attempts to keep the scene afloat, by applying a minor surcharge to their ticket prices, which supports independent venues.
He also participated, raising over £100k on his recent tour to help 38 small stages across Britain.
These funds helped spaces that were facing possible closure due to issues arising from flooding, blazes and bereavements, as well as permit problems, court cases and neighbor objections.
Some locations received financial assistance in modernizing infrastructure and technical equipment that directly benefitted performers and audiences.
"The notion that funds from performances in major spaces helps the independent spots, where it kicks off for performers like me, is just common sense," Fender has commented.
He is not the first artist to donate his Mercury Prize prize money to good deeds.
In the band received the award in the year 1996 for their release their work, lead singer Jarvis Cocker stated that the act would give their winnings to the charity War Child.
In 2002, musician the artist split her prize among several charities, including the NSPCC and a Sickle Cell charity.
"And I donated a £1,000 to Highgate Newtown, to their classes, because I did gymnastics when I was younger and they needed updated gear," she shared with outlets.
In recent years, they contributed their prize money to the local youth club that supported their band, in addition to other grassroots music organisations.
Also the 1994 recipients the group donated their winnings to a multiple sclerosis charity after a friend was diagnosed the illness.
"Receiving the award was quite enough," stated singer the singer. "The prize was the cherry on top but we didn't need the extra, because we had the cake. So our victory affected somebody else's life."
Last week, the Music Venues Trust shared it had protected several local spots in that region, by transferring them to public stewardship.
One venue in that area and the second in Bristol were acquired under the public acquisition program, which is backed by a national body and music fans who purchase "ownership units" in the venues.